| 1 | Greenville Technical College | Greenville | Public, 4-year | 1,299 |
| 2 | Tri-County Technical College | Pendleton | Public, 2-year | 1,294 |
| 3 | Trident Technical College | Charleston | Public, 2-year | 630 |
| 4 | Spartanburg Community College | Spartanburg | Public, 2-year | 470 |
| 5 | York Technical College | Rock Hill | Public, 2-year | 469 |
| 6 | Midlands Technical College | West Columbia | Public, 2-year | 444 |
| 7 | Horry-Georgetown Technical College | Conway | Public, 2-year | 301 |
| 8 | Piedmont Technical College | Greenwood | Public, 2-year | 292 |
| 9 | Northeastern Technical College | Cheraw | Public, 2-year | 262 |
| 10 | University of South Carolina-Sumter | Sumter | Public, 2-year | 187 |
| 11 | Spartanburg Methodist College | Spartanburg | Private nonprofit, 4-year | 174 |
| 12 | Orangeburg Calhoun Technical College | Orangeburg | Public, 2-year | 165 |
| 13 | University of South Carolina-Lancaster | Lancaster | Public, 2-year | 128 |
| 14 | University of South Carolina-Union | Union | Public, 2-year | 121 |
| 15 | Central Carolina Technical College | Sumter | Public, 2-year | 106 |
| 16 | University of South Carolina-Salkehatchie | Allendale | Public, 2-year | 99 |
| 17 | Aiken Technical College | Graniteville | Public, 2-year | 86 |
| 18 | Technical College of the Lowcountry | Beaufort | Public, 2-year | 81 |
| 19 | Florence-Darlington Technical College | Florence | Public, 2-year | 58 |
| 20 | Denmark Technical College | Denmark | Public, 2-year | 57 |
| 21 | University of South Carolina-Upstate | Spartanburg | Public, 4-year | 55 |
| 22 | Coastal Carolina University | Conway | Public, 4-year | 54 |
| 23 | Limestone University | Gaffney | Private nonprofit, 4-year | 39 |
| 24 | Columbia International University | Columbia | Private nonprofit, 4-year | 18 |
| 25 | University of South Carolina Beaufort | Bluffton | Public, 4-year | 18 |